国立医薬品食品衛生研究所 安全性生物試験研究センター 総合評価研究室


ホーム

メンバー

研究・業務
研究内容
業務内容
行政活動

リソース・リンク
学会・誌上発表
SIAM/CoCAM
化学物質情報リンク
 

学会・誌上発表


誌上発表 2002年〜2005年


2005年

Ema, M., Hara, H., Matsumoto, M., Hirose, A., Kamata, E. (2005). Evaluation of developmental toxicity of 1-butanol given to rats in drinking water throughout pregnancy. Food Chem Toxicol 43(2): 325-31.

Hasegawa, R., Hirata-Koizumi, M., Takahashi, M., Kamata, E., Ema, M. (2005). Comparative susceptibility of newborn and young rats to six industrial chemicals. Congenit Anom (Kyoto) 45(4): 137-45.

Hayashi, M., Kamata, E., Hirose, A., Takahashi, M., Morita, T., Ema, M. (2005). In silico assessment of chemical mutagenesis in comparison with results of Salmonella microsome assay on 909 chemicals. Mutat Res 588(2): 129-35.

Hirata-Koizumi, M., Hamamura, M., Furukawa, H., Fukuda, N., Ito, Y., Wako, Y., Yamashita, K., Takahashi, M., Kamata, E., Ema, M., Hasegawa, R. (2005). Elevated susceptibility of newborn as compared with young rats to 2-tert-butylphenol and 2,4-di-tert-butylphenol toxicity. Congenit Anom (Kyoto) 45(4): 146-53.

Hirata-Koizumi, M., Kusuoka, O., Nishimura, N., Wada, H., Ogata, H., Fukuda, N., Ito, Y., Kamata, E., Ema, M., Hasegawa, R. (2005). Susceptibility of newborn rats to hepatotoxicity of 1,3-dibromopropane and 1,1,2,2-tetrabromoethane, compared with young rats. J Toxicol Sci 30(1): 29-42.

Matsumoto, M., Suzuki, M., Kawahara, K., Sugaya, Y., Ema, M. (2005). OECD High Production Volume Chemicals Programme: Summary of 20th SIDS Initial Assessment Meeting. ChemoBio Integrated Management 1(3): 445-453.

Matsumoto, M., Tanaka, R., Kawahara, K., Sugaya, Y., Ema, M. (2005). OECD High Production Volume Chemicals Programme: Summary of 19th SIDS Initial Assessment Meeting. ChemoBio Integrated Management 1(2): 280-288.

Takahashi, M., Hirata-Koizumi, M., Matsumoto, M., Hirose, A., Kamata, E., Hasegawa, R., Ema, M. (2005). Progress on OECD chemicals programme (6)− SIAM 14 in Paris, 2002− ChemoBio Integrated Management 1(1): 46-55.

Takahashi, M., Hirata-Koizumi, M., Matsumoto, M., Hirose, A., Kamata, E., Hasegawa, R., Ema, M. (2005). [Progress on OECD chemicals programme (7)--SIAM 15 in Boston, 2002]. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku 123: 46-52 .

2004年

Ema, M., Harazono, A., Fujii, S., Kawashima, K. (2004). Evaluation of developmental toxicity of [beta]-thujaplicin (hinokitiol) following oral administration during organogenesis in rats. Food and Chemical Toxicology 42(3): 465-470.

Fukuda, N., Ito, Y., Yamaguchi, M., Mitumori, K., Koizumi, M., Hasegawa, R., Kamata, E., Ema, M. (2004). Unexpected nephrotoxicity induced by tetrabromobisphenol A in newborn rats. Toxicol Lett 150(2): 145-55.

Fukui, Y., Ema, M., Fujiwara, M., Higuchi, H., Inouye, M., Iwase, T., Kihara, T., Nishimura, T., Oi, A., Ooshima, Y., Otani, H., Shinomiya, M., Sugioka, K., Yamano, T., Yamashita, K. H., Tanimura, T. (2004). Comments from the Behavioral Teratology Committee of the Japanese Teratology Society on OECD guideline for the testing of chemicals, proposal for a new guideline 426, developmental neurotoxicity study, draft document (September 2003). Congenit Anom (Kyoto) 44(3): 172-7.

Hasegawa, R., Koizumi, M., Hirose, A. (2004). Principles of risk assessment for determining the safety of chemicals: recent assessment of residual solvents in drugs and di(2-ethylhexyl) phthalate. Congenit Anom (Kyoto) 44(2): 51-9.

Hirose, A., Ema, M. (2004). [Recent TDI derivation of dioxin based on the reproductive and developmental toxicity]. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku 122: 56-61.

Hirose, A., Hasegawa, R., Nishikawa, A., Takahashi, M., Ema, M. (2004). Revision and establishment of Japanese drinking water quality guidelines for di(2-ethylhexyl) phthalate, toluene and vinyl chloride -- differences from the latest WHO guideline drafts. J Toxicol Sci 29(5): 535-9.

Takahashi, M., Hirata, M., Matsumoto, M., Hirose, A., Kamata, E., Hasegawa, R., Ema, M. (2004). [Progress on OECD chemicals programme]. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku 122: 37-42.

Takahashi, M., Ogata, H., Izumi, H., Yamashita, K., Takechi, M., Hirata-Koizumi, M., Kamata, E., Hasegawa, R., Ema, M. (2004). Comparative toxicity study of 2,4,6-trinitrophenol (picric acid) in newborn and young rats. Congenit Anom (Kyoto) 44(4): 204-14.

広瀬明彦 (2004). ダイオキシン類の耐用摂取量の設定と安全性評価. イルシー 79: 28-34 .

2003年

Ema, M., Harazono, A., Hirose, A., Kamata, E. (2003). Protective effects of progesterone on implantation failure induced by dibutyltin dichloride in rats. Toxicol Lett 143(2): 233-8.

Ema, M., Miyawaki, E., Hirose, A., Kamata, E. (2003). Decreased anogenital distance and increased incidence of undescended testes in fetuses of rats given monobenzyl phthalate, a major metabolite of butyl benzyl phthalate. Reprod Toxicol 17(4): 407-12.

Harazono, A., Ema, M. (2003). Suppression of decidual cell response induced by dibutyltin dichloride in pseudopregnant rats: as a cause of early embryonic loss. Reprod Toxicol 17(4): 393-9.

Hirose, A., Ema, M., Hasegawa, R. (2003). [Safety evaluation of chemicals using bibliographic databases for their effects on gene expression profiles]. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku 121: 124-7.

Koizumi, M., Noda, A., Ito, Y., Furukawa, M., Fujii, S., Kamata, E., Ema, M., Hasegawa, R. (2003). Higher susceptibility of newborn than young rats to 3-methylphenol. J Toxicol Sci 28(2): 59-70.

広瀬明彦, 江馬真, 鎌田栄一, 小泉睦子, 長谷川隆一 (2003). ビスフェノールAの内分泌かく乱作用のヒトへの健康影響評価. 日本食品化学学会誌 10(1): 1-12 .

2002年

Koizumi, M., Nishimura, N., Enami, T., Sunaga, M., Horikawa, H., Kamata, E., Hasegawa, R. (2002). Comparative toxicity study of 3-aminophenol in newborn and young rats. J Toxicol Sci 27(5): 411-21.

Koizumi, M., Ohno, Y., Hirose, M., Ema, M., Inoue, T., Hasegawa, R. (2002). [Toxicity Evaluation of DINP and Estimation of The Tolerable Daily Intake]. Japanese journal of food chemistry 9(2): 39-45.

Niho, N., Shibutani, M., Toyoda, K., Sato, H., Hirose, A., Imaida, K., Takahashi, M., Hayashi, Y., Hirose, M. (2002). Dose- and time-response studies of sodium o-phenylphenate urinary bladder carcinogenicity in rats. Food Chem Toxicol 40(5): 715-22.

鎌田栄一 (2002). 子供たちにおくる安心の化学 子供に対する化学物質の安全性評価 評価手法の現状とリスク管理. 化学と工業 55(6): 640-644.

広瀬明彦, 西川秋佳, 紅林秀雄, 山田雅巳, 長谷川隆一, 江馬真 (2002). メチル-tert-ブチルエーテル(MTBE)の毒性情報. 水環境学会誌 25(8): 491-496.

江馬真 (2002). 有機スズの生殖発生毒性. Endocr Disrupter News Lett 4(4): 6 .


安全性生物試験研究センター

国立衛研

↑ページのトップへ戻る

 

  最終更新日 2012/02/01